Is Troxerutin safe in cosmetics?
Troxerutin has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Troxerutin
Also known as: BRN 4778232, EINECS 230-389-4, Factor P-zyma, Tris(hydroxyethyl)rutin, Tris(hydroxyethyl)rutoside (+15 more)
INCI: TROXERUTIN
Troxerutin (CAS 7085-55-4) is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7085-55-4 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
InChIKey
IYVFNTXFRYQLRP-VVSTWUKXSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted under general cosmetic provisions; also used as pharmaceutical ingredient (Vitamin P4 derivative)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Troxerutin.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Troxerutin.
Known Synonyms
BRN 4778232
EINECS 230-389-4
Factor P-zyma
Tris(hydroxyethyl)rutin
Tris(hydroxyethyl)rutoside
Venoruton P4
7,3',4'-Tris(O-(2-hydroxyethyl)rutin
Veno SL
Venaroid
Pur-Rutin
Troxarutin-ratiopharm
Troxarutin
Helveton
Pherarutin
Posorutin
Troksevazin
Veinamitol Pulver
Trihydroxyethylrutoside
Troxerutina
Troxerutine
Chemical Function
Softener and conditioner
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Canada; Personal care; Substances in PCP - Canada (4/2014)
pharmaceutical
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
TROXERUTIN
ChEMBL ID
CHEMBL3182320
Max Phase
4
Frequently Asked Questions
Is Troxerutin allowed in the EU?
Troxerutin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Troxerutin do in cosmetics?
Troxerutin functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 7085-55-4.
Is Troxerutin used outside cosmetics?
Troxerutin also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Troxerutin compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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