Good Cosmetic Ingredient GHS Classified Dermal Penetration

Vaseline (Petrolatum)

Also known as: Caswell No. 645A, EINECS 232-373-2, EPA Pesticide Chemical Code 598400, Extra amber, Mineral fat (+15 more)

INCI: PETROLATUM

Vaseline (Petrolatum) (CAS 8009-03-8) is a cosmetic cosmetic ingredient functioning as Skin conditioning, skin protecting, emollient, occlusive agent. NOAEL 125 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 8009-03-8 →

Auto-generated CPSR Part A draft with source citations

Cross-Vertical Regulatory Divergence

Vaseline (Petrolatum) is classified GHS Danger (H350) in the chemicals database but is allowed in EU cosmetics.

Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code

CAS Number

8009-03-8

View industrial chemical safety profile →

Function

Skin conditioning, skin protecting, emollient, occlusive agent

Safety Rating

GOOD

Chemistry & Identifiers

EC Number

232-373-2

UNII: 4T6H12BN9U Wikidata: Q457239

Regulatory Status

EU EU Status permitted

US US Status permitted

US Notes Permitted; FDA-approved OTC skin protectant (21 CFR 347); CIR-assessed as safe; GRAS for food contact

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Vaseline (Petrolatum).

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Routes of Exposure

The substance can be absorbed into the body by ingestion.

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Vaseline (Petrolatum) across SCCS product categories, with measured dermal absorption where available.

Dermal Penetration Profile

Skin absorption and penetration characteristics of Vaseline (Petrolatum), relevant to systemic exposure and MoS calculations.

Absorption %

Penetration Level

surface

Penetration Depth

surface only

Molecular Weight

Variable Da

Log P

n/a

Systemic Absorption

Topical Bioavailability

Safety Margin Factor

none

Source: CIR

EU CLP Annex VI Harmonized Classification

Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.

Signal Word

Danger

Pictograms

Health Hazard

Hazard Class and Category

Carc. 1B

Hazard Statements

H350 May cause cancer

Inserted via ATP: ATP02

HRIPT Human Patch Test Studies

1 human repeat insult patch test aggregated from dermatological literature.

Test Type	N	Sensitized	Dose µg/cm²	NESIL µg/cm²	Potency
HMT	-	0	15517.24	-	-

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type

Full

Tonnage Band

100,000 - 1,000,000 tonnes

Substance Type

SUBSTANCE; GROUP

SVHC Candidate

Hazard classification: Restricted (Annex XVII)

EU CosIng Annex Listing

European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.

Annex II — Prohibited

Ref: 904

(EC) 2009/1223

CMR: Carcinogenic Cat. 1B()

Expanded Jurisdictional Detail

Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.

SA Saudi SFDA (II - Prohibited)

BRIN Brazil/India Cosmetics

Brazil: Prohibited

India: Prohibited (GNRAS)

Typical Use Concentrations

Reported concentration ranges per product category from SCCS/CIR/industry sources.

Product Category	Typical Range	Max Reported	Source
Lip Balm	5–40	100	CIR/VCRP
Body Lotion	2–10	25	CIR/VCRP

Additional Ingredient Properties

10 property records from structured ingredient metadata.

baby_pediatric

{"cas_number": "8009-03-8", "ingredient_class": "moisturizer_baby", "pediatric_safety_rating": "excellent", "minimum_age_months": "0", "neonatal_safe": "yes", "premature_infant_safe": "yes", "skin_barrier_maturity_consideration": "GOLD STANDARD: Occlusive, barrier repair, extensively tested", "transepidermal_absorption_risk_pediatric": "very_low", "dose_per_kg_body_weight_concern": "Non-absorbed",…

concentration

{"min_concentration_pct": "5.0", "max_concentration_pct": "40.0", "typical_concentration_pct": "20.0", "product_type": "Body Butter", "function_at_concentration": "Occlusive", "source": "FDA OTC Monograph"}

dermal_absorption

{"molecular_weight_da": "Variable", "skin_penetration_level": "surface", "penetration_depth": "surface only", "absorption_pct": "0", "systemic_absorption": "no", "penetration_enhancer": "no", "occlusion_effect": "yes", "vehicle_dependent": "no", "skin_barrier_effect": "neutral", "bioavailability_topical_pct": "0", "source": "CIR"}

emulsion_hlb

{"hlb_required_as_emulsifier": "no", "hlb_required_of_oil_phase": "7-9", "co_emulsifier_pairs": "sorbitan_oleate,polysorbate_60", "optimal_oil_phase_pct": "20-50", "optimal_water_phase_pct": "50-80", "droplet_size_range_um": "10-80", "creaming_resistance": "moderate", "coalescence_resistance": "excellent", "ostwald_ripening_resistance": "excellent", "freeze_thaw_stability": "excellent", "rheology_…

hair_care

{"hair_function": "moisturizing", "hair_type_suitability": "coarse", "curl_pattern_suitability": "all", "porosity_suitability": "low", "protein_sensitivity": "neutral", "moisture_protein_balance": "no", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "no", "color_safe": "neutral", "ker…

pediatric_safety

{"safe_for_newborn_0_6m": "yes", "safe_for_infant_6_12m": "yes", "safe_for_toddler_1_3y": "yes", "safe_for_child_3_12y": "yes", "safe_for_teen_12_18y": "yes", "pediatric_max_concentration_pct": "100.0", "adult_max_concentration_pct": "100.0", "pediatric_dermal_absorption_factor": "minimal", "oral_ingestion_risk": "low", "diaper_area_safe": "yes", "pediatric_allergy_prevalence": "low", "banned_in_c…

pregnancy_detail

{"pregnancy_safe": "yes", "breastfeeding_safe": "yes", "risk_category": "not-rated", "reason": "Safe; occlusive; USP grade recommended", "source": "dermatology literature"}

sensory

{"silky": "waxy", "smooth, glides easily": "heavy, occlusive", "dry-touch, non-greasy": "greasy, protected", "instant": "very-slow", "low": "very-high", "w/o": "w/o", "no": "yes", "yes": "yes", "light-diffusing": "high-shine", "1.40": "1.47", "transparent": "translucent", "colorless": "white", "light": "very-rich", "synthetic": "petrochemical"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories

Anti-static agent Binder Corrosion inhibitor Emulsifier Flavouring and nutrient Humectant Lubricating agent Softener and conditioner Solubility enhancer Solvent

Regulatory List Membership (4)

EU Banned in Cosmetics EU Regulated in Personal Care FDA Substances Added to Food (EAFUS) EU CosIng Cosmetics Ingredient Database

Expert Verdict

Expert safety assessment and concern-level summary for Vaseline (Petrolatum).

Regulatory Flags

eu_banned_cosmetics fda_food_additive eu_cosing_listed jecfa_concern

Known Synonyms

Caswell No. 645A EINECS 232-373-2 EPA Pesticide Chemical Code 598400 Extra amber Mineral fat Mineral wax Petrolatum, amber Petrolatum USP Petrolatum, yellow Protopet, alba Protopet, white 1S Protopet, white 2L Saxoline Vasoliment White petrolatum USP White petroleum jelly Yellow petrolatum UNII-4T6H12BN9U Petrolatum, white Soft paraffin

Chemical Function

Softener and conditioner

Regulatory Lists

inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides inert_ingredient; non_food_use; Pesticides Europe; Personal care - liniment Europe; Personal care Europe; Personal care food_additive; Substances Added to Food (formerly EAFUS) (2/2019) Canada; pharmaceutical Canada; pharmaceutical Europe; Personal care - oral and dental care - teeth whitener banned; Europe; Personal care Cleaning products and household care - shoes; Europe Cleaning products and household care - shoes; Europe Europe; Personal care - make-up and related Europe; Personal care - make-up and related drinking_water; Europe; manufacturing; plastic_additive

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations

905

View full pharmaceutical profile →

Frequently Asked Questions

Is Vaseline (Petrolatum) safe in cosmetics?

Vaseline (Petrolatum) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Vaseline (Petrolatum) allowed in the EU?

Vaseline (Petrolatum) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Vaseline (Petrolatum) do in cosmetics?

Vaseline (Petrolatum) functions as: Skin conditioning, skin protecting, emollient, occlusive agent. It is classified as a cosmetic ingredient in our database. CAS number: 8009-03-8.

Is Vaseline (Petrolatum) used outside cosmetics?

Vaseline (Petrolatum) also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Vaseline (Petrolatum) have different safety status in cosmetics vs industrial chemicals?

Vaseline (Petrolatum) is classified GHS Danger (H350) in the chemicals database but is allowed in EU cosmetics.

Compliance Tools

Check Vaseline (Petrolatum) compliance across multiple jurisdictions:

Ingredient Decoder

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82 Allergen Checker

Check for EU declarable fragrance allergens

Substance Compliance

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MoS Calculator

Calculate Margin of Safety using SCCS methodology

Heavy Metal Limits

Compare limits across jurisdictions

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Petrolatum

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Emollient, occlusive, skin protectant...

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