Vinca Major Extract

INCI: VINCA MAJOR EXTRACT

CAS Number
84012-40-8
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted; no CIR report

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains pharmacologically active indole alkaloids. Vinca alkaloids are potent pharmaceutical agents. Concentration-dependent safety โ€” must be used at very low levels. No formal CIR/SCCS assessment. Pregnancy caution warranted

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Vinca Major Extract safe in cosmetics?

Contains pharmacologically active indole alkaloids. Vinca alkaloids are potent pharmaceutical agents. Concentration-dependent safety โ€” must be used at very low levels. No formal CIR/SCCS assessment. Pregnancy caution warranted The EU classifies Vinca Major Extract as "permitted". Safety rating: MODERATE.

Is Vinca Major Extract allowed in the EU?

Vinca Major Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Vinca Major Extract do in cosmetics?

Vinca Major Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84012-40-8.

What is the Margin of Safety for Vinca Major Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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