Willow Bark Extract

INCI: SALIX ALBA BARK EXTRACT

CAS Number
84082-82-6
Function
Natural salicin source (BHA precursor)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted by FDA for cosmetic use. CIR reviewed salicylates in 2019 -- safe when formulated non-irritating and non-sensitizing. Salix alba bark-specific CIR assessment ongoing (2024-2025, 1082 formulations, <=1.1% leave-on), not yet finalized.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Willow bark extract (CAS 84082-82-6) is permitted in the EU and not restricted by the FDA for cosmetic use; CIR determined salicylates safe when formulated non-irritating and non-sensitizing, with Salix alba-specific assessment ongoing.

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Concern Level: Low

Regulatory Flags

salicylate-sensitivity aspirin-cross-reactivity in-vitro-sensitizer cir-review-pending patch-test-advised eu_children_restricted

Frequently Asked Questions

Is Willow Bark Extract safe in cosmetics?

Willow bark extract (CAS 84082-82-6) is permitted in the EU and not restricted by the FDA for cosmetic use; CIR determined salicylates safe when formulated non-irritating and non-sensitizing, with Salix alba-specific assessment ongoing. The EU classifies Willow Bark Extract as "permitted". Safety rating: GOOD.

Is Willow Bark Extract allowed in the EU?

Willow Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Willow Bark Extract do in cosmetics?

Willow Bark Extract functions as: Natural salicin source (BHA precursor). It is classified as a Active Ingredient in our database. CAS number: 84082-82-6.

What is the Margin of Safety for Willow Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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