Good Active Ingredient GHS Classified

Gluconic Acid

INCI: GLUCONIC ACID

CAS Number
526-95-4
Function
Exfoliant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 50%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR: S - IJT 38(S1):5-38, 2019

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Hazard Statements
No hazard classification according to GHS criteria

Expert Verdict

Good safety profile with established use as an exfoliant; generally considered safe for cosmetic applications.

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Concern Level: Low

Regulatory Flags

epa_safer_alternative fda_food_additive

Frequently Asked Questions

Is Gluconic Acid safe in cosmetics?

Good safety profile with established use as an exfoliant; generally considered safe for cosmetic applications. The EU classifies Gluconic Acid as "permitted". Safety rating: GOOD.

Is Gluconic Acid allowed in the EU?

Gluconic Acid EU regulatory status: permitted. Maximum allowed concentration: 50%. This is based on EU Regulation 1223/2009 and its amendments.

What does Gluconic Acid do in cosmetics?

Gluconic Acid functions as: Exfoliant. It is classified as a Active Ingredient in our database. CAS number: 526-95-4.

What is the Margin of Safety for Gluconic Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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