Moderate Cosmetic Ingredient Sensitization Data

Wormwood Extract

INCI: ARTEMISIA ABSINTHIUM EXTRACT

CAS Number
84929-19-1
Function
Skin conditioning, fragrance
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted by FDA for cosmetic use. Artemisia extract is listed as GRAS for food with thujone-free specification.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Wormwood Extract based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
compositae-group
Reaction Type
contact-dermatitis

Source: IVDK; literature review

Expert Verdict

Thujone content is neurotoxic at high doses and must be quantified and controlled. Sesquiterpene lactones are potent contact sensitizers. Compositae allergy cross-reactivity risk exists. Essential oil chemotype variability affects safety profile.

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Concern Level: High

Regulatory Flags

plant-extract essential-oil potential-allergen fragrance-component

Frequently Asked Questions

Is Wormwood Extract safe in cosmetics?

Thujone content is neurotoxic at high doses and must be quantified and controlled. Sesquiterpene lactones are potent contact sensitizers. Compositae allergy cross-reactivity risk exists. Essential oil chemotype variability affects safety profile. The EU classifies Wormwood Extract as "restricted". Safety rating: MODERATE.

Is Wormwood Extract allowed in the EU?

Wormwood Extract EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Wormwood Extract do in cosmetics?

Wormwood Extract functions as: Skin conditioning, fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 84929-19-1.

What is the Margin of Safety for Wormwood Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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