Good Cosmetic Ingredient NOAEL Data

ZINGIBER OFFICINALE ROOT OIL

Also known as: Zingiber officinale oil, Oils, ginger

ZINGIBER OFFICINALE ROOT OIL (CAS 8007-08-7) is a cosmetic cosmetic ingredient functioning as Fragrance, Perfuming, Skin Conditioning, Tonic. Reported NOAEL =500 mg/kg bw/day in Rat (EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 8007-08-7 →

Auto-generated CPSR Part A draft with source citations
Function
Fragrance, Perfuming, Skin Conditioning, Tonic
Safety Rating
GOOD

Chemistry & Identifiers

Regulatory Status

EU EU Status permitted
US US Status Not specifically regulated

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Toxicological Studies

2 study endpoints found for ZINGIBER OFFICINALE ROOT OIL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =500 mg/kg bw/day oral: gavage Rat subchronic EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx
NOAEL =500 mg/kg bw/day oral: gavage Rat subchronic EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx

EPA ToxValDB — Toxicity Values

1 toxicity value from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
LD50 >5000 mg/kg Rat oral - TEST

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Deodorizer Flavouring and nutrient Fragrance Humectant Softener and conditioner
Regulatory List Membership (3)
IFRA Fragrance Transparency List FDA Substances Added to Food (EAFUS) Consumer Product Chemical

Expert Verdict

Expert safety assessment and concern-level summary for ZINGIBER OFFICINALE ROOT OIL.

Regulatory Flags

cosing-sourced eu-permitted skin-conditioning fragrance needs-enrichment ifra_fragrance fda_food_additive

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to ZINGIBER OFFICINALE ROOT OIL by CAS number or substance name.

Studies
2
Lowest NOAEL
500 mg/kg bw/day
Highest NOAEL
500 mg/kg bw/day
EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx

Known Synonyms

Zingiber officinale oil Oils, ginger

Chemical Function

Fragrance Deodorizer Humectant Softener and conditioner

Regulatory Lists

IFRA Transparency IFRA Transparency IFRA Transparency Europe; Personal care - body oil IFRA Transparency Canada; pharmaceutical Canada; pharmaceutical consumer_product IFRA Transparency IFRA Transparency IFRA Transparency food_additive; Substances Added to Food (formerly EAFUS) (2/2019) inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides

Australian Status

AICIS status: listed

Frequently Asked Questions

Is ZINGIBER OFFICINALE ROOT OIL safe in cosmetics?

ZINGIBER OFFICINALE ROOT OIL has a safety rating of "GOOD" in our database. EU status: permitted. 2 toxicological study endpoint(s) are available in our database.

Is ZINGIBER OFFICINALE ROOT OIL allowed in the EU?

ZINGIBER OFFICINALE ROOT OIL EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does ZINGIBER OFFICINALE ROOT OIL do in cosmetics?

ZINGIBER OFFICINALE ROOT OIL functions as: Fragrance, Perfuming, Skin Conditioning, Tonic. It is classified as a cosmetic ingredient in our database. CAS number: 8007-08-7.

What is the NOAEL for ZINGIBER OFFICINALE ROOT OIL?

The NOAEL (No Observed Adverse Effect Level) for ZINGIBER OFFICINALE ROOT OIL is =500 mg/kg bw/day based on a subchronic study via oral: gavage route in Rat. A total of 2 study endpoints are available. Source: EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx.

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