Is 1,3-Bis-(2,4-Diaminophenoxy)Propane safe in cosmetics?
1,3-Bis-(2,4-Diaminophenoxy)Propane has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
MODERATE
Cosmetic Ingredient
1,3-Bis-(2,4-Diaminophenoxy)Propane
INCI: 1,3-BIS-(2,4-DIAMINOPHENOXY)PROPANE
1,3-Bis-(2,4-Diaminophenoxy)Propane (CAS 81892-72-0 (free base); 74918-21-1 (tetrahydrochloride salt)) is a cosmetic cosmetic ingredient functioning as Oxidative and non-oxidative hair dye (Colipa A079). EU Regulation 1223/2009 status: prohibited, max 2.0%. Industrial safety data is also available in the chemical safety database.
CAS Number
81892-72-0 (free base); 74918-21-1 (tetrahydrochloride salt)
View industrial chemical safety profile →
Function
Oxidative and non-oxidative hair dye (Colipa A079)
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
prohibited
EU Max Conc.
2.0%
US US Status
permitted
US Notes
Permitted for use in hair dyes under FDA coal-tar hair dye exemption (21 USC §361(a)) with caution labeling
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 1,3-Bis-(2,4-Diaminophenoxy)Propane.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for 1,3-Bis-(2,4-Diaminophenoxy)Propane — not a computed safety verdict. See the sourced toxicological data above.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to 1,3-Bis-(2,4-Diaminophenoxy)Propane by CAS number or substance name.
Studies
8
Lowest NOAEL
40 mg/kg bw/day
Highest NOAEL
180 mg/kg bw/day
SCCS Opinion
Frequently Asked Questions
Is 1,3-Bis-(2,4-Diaminophenoxy)Propane allowed in the EU?
1,3-Bis-(2,4-Diaminophenoxy)Propane EU regulatory status: prohibited. Maximum allowed concentration: 2.0%. This is based on EU Regulation 1223/2009 and its amendments.
What does 1,3-Bis-(2,4-Diaminophenoxy)Propane do in cosmetics?
1,3-Bis-(2,4-Diaminophenoxy)Propane functions as: Oxidative and non-oxidative hair dye (Colipa A079). It is classified as a cosmetic ingredient in our database. CAS number: 81892-72-0 (free base); 74918-21-1 (tetrahydrochloride salt).
Compliance Tools
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Substance Compliance
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MoS Calculator
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