Moderate Cosmetic Ingredient

1,6-HDI/Polyvinyl Alcohol/Ethylenediamine Crosspolymer

INCI: 1,6-HDI/POLYVINYL ALCOHOL/ETHYLENEDIAMINE CROSSPOLYMER

CAS Number
Not assigned a single CAS (high MW crosspolymer)
Function
Film forming / viscosity controlling
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR assessed HDI polymers as a group — 7 were declared safe as used; 12 had insufficient data. This specific crosspolymer may fall in the insufficient-data category depending on MW and residual monomer content.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Residual monomer HDI is a leading cause of occupational asthma. Must verify: (1) MW >1000 Da, (2) residual free HDI quantified and minimized, (3) inhalation exposure controlled in powder/spray applications.

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Concern Level: Moderate

Frequently Asked Questions

Is 1,6-HDI/Polyvinyl Alcohol/Ethylenediamine Crosspolymer safe in cosmetics?

Residual monomer HDI is a leading cause of occupational asthma. Must verify: (1) MW >1000 Da, (2) residual free HDI quantified and minimized, (3) inhalation exposure controlled in powder/spray applications. The EU classifies 1,6-HDI/Polyvinyl Alcohol/Ethylenediamine Crosspolymer as "permitted". Safety rating: MODERATE.

Is 1,6-HDI/Polyvinyl Alcohol/Ethylenediamine Crosspolymer allowed in the EU?

1,6-HDI/Polyvinyl Alcohol/Ethylenediamine Crosspolymer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 1,6-HDI/Polyvinyl Alcohol/Ethylenediamine Crosspolymer do in cosmetics?

1,6-HDI/Polyvinyl Alcohol/Ethylenediamine Crosspolymer functions as: Film forming / viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned a single CAS (high MW crosspolymer).

What is the Margin of Safety for 1,6-HDI/Polyvinyl Alcohol/Ethylenediamine Crosspolymer?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check 1,6-HDI/Polyvinyl Alcohol/Ethylenediamine Crosspolymer compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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