Poor Cosmetic Ingredient GHS Classified

1,6-Hexanediamine

INCI: HEXAMETHYLENEDIAMINE

CAS Number
124-09-4
Function
Industrial chemical (nylon monomer); not a typical cosmetic active
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status prohibited
US Notes Not a recognized cosmetic ingredient; no FDA cosmetic approval

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated.
Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

Expert Verdict

Corrosive (Skin Corr. 1B) with severe eye damage, acute toxicity by all routes, and potential reproductive toxicity concerns. Not suitable for cosmetic use.

⚠️
Concern Level: High

Frequently Asked Questions

Is 1,6-Hexanediamine safe in cosmetics?

Corrosive (Skin Corr. 1B) with severe eye damage, acute toxicity by all routes, and potential reproductive toxicity concerns. Not suitable for cosmetic use. The EU classifies 1,6-Hexanediamine as "prohibited". Safety rating: POOR.

Is 1,6-Hexanediamine allowed in the EU?

1,6-Hexanediamine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 1,6-Hexanediamine do in cosmetics?

1,6-Hexanediamine functions as: Industrial chemical (nylon monomer); not a typical cosmetic active. It is classified as a cosmetic ingredient in our database. CAS number: 124-09-4.

What is the Margin of Safety for 1,6-Hexanediamine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check 1,6-Hexanediamine compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Methylbutylphenyl Octyloxybenzoate
Moderate
Cetyl Tranexamate HCl
Moderate
Polyquaternium-33
Good
Dioleoylethyl Hydroxyethylmonium Methosulfate
Good
Hypochlorous Acid
Moderate
Browse all 30,000+ ingredients →
📱

Is 1,6-Hexanediamine in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for 1,6-Hexanediamine in your formulation.

Ingredient Decoder MoS Calculator