Is 2,5-DIMETHYLPYRAZINE safe in cosmetics?
2,5-DIMETHYLPYRAZINE has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
2,5-DIMETHYLPYRAZINE
Also known as: 2,5-Dimethyl-1,4-diazine, 2,5-Dimethylparadiazine, 2,5-Dimethylpiazine, EINECS 204-618-3, FEMA No. 3272 (+6 more)
2,5-DIMETHYLPYRAZINE (CAS 123-32-0) is a cosmetic cosmetic ingredient functioning as Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 123-32-0 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
2,5-dimethylpyrazine
InChIKey
LCZUOKDVTBMCMX-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (4)
JECFA Number
766
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2,5-DIMETHYL-1,4-DIAZINE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/51 | FAS 48-JECFA 57/135
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
KETINE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/51 | FAS 48-JECFA 57/135
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2,5-DIMETHYLPYRAZINE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/51 | FAS 48-JECFA 57/135
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for 2,5-DIMETHYLPYRAZINE.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
2,5-Dimethyl-1,4-diazine
2,5-Dimethylparadiazine
2,5-Dimethylpiazine
EINECS 204-618-3
FEMA No. 3272
UNII-V99Y0MUY1Q
2, 5-Dimethylpyrazine
2,5-Dimethyl pyrazine
2,5-Dimethyl-Pyrazine
FEMA 3272
PYRAZINE,2,5-DIMETHYL
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Australia; Food and drug - smoking-related products
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL94709
Frequently Asked Questions
Is 2,5-DIMETHYLPYRAZINE allowed in the EU?
2,5-DIMETHYLPYRAZINE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,5-DIMETHYLPYRAZINE do in cosmetics?
2,5-DIMETHYLPYRAZINE functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 123-32-0.
Is 2,5-DIMETHYLPYRAZINE used outside cosmetics?
2,5-DIMETHYLPYRAZINE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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MoS Calculator
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