Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
5 study endpoints found for 2-Acetonaphthone. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 36.9 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 36.9 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 33 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 250 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 225 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Naphthalene backbone — monitor for phototoxicity potential; IFRA status should be checked for fragrance-specific use limits.
Regulatory Flags
Frequently Asked Questions
Is 2-Acetonaphthone safe in cosmetics?
Naphthalene backbone — monitor for phototoxicity potential; IFRA status should be checked for fragrance-specific use limits. The EU classifies 2-Acetonaphthone as "permitted". Safety rating: MODERATE. 5 toxicological study endpoint(s) are available in our database.
Is 2-Acetonaphthone allowed in the EU?
2-Acetonaphthone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Acetonaphthone do in cosmetics?
2-Acetonaphthone functions as: Masking, Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 93-08-3.
What is the Margin of Safety for 2-Acetonaphthone?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 2-Acetonaphthone?
The NOAEL (No Observed Adverse Effect Level) for 2-Acetonaphthone is 36.9 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 5 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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