Is 2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol safe in cosmetics?
2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol
Also known as: Myrcenol, dihydro, 7-Octen-2-ol, 2-methyl-6-methylene-, dihydro deriv., EINECS 258-432-2
2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol (CAS 53219-21-9) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 53219-21-9 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2,6-dimethyloct-7-en-2-ol
InChIKey
XSNQECSCDATQEL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not individually regulated by FDA; falls under general fragrance safety provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol.
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization AOP Dashboard
Adverse Outcome Pathway data across 5 assays (DPRA, KeratinoSens, hCLAT, LLNA, NESIL) aggregated from public sources.
NESIL
1033 µg/cm²
GHS: 1B
Human: positive
Source: HPPT: [611] RIFM (1973): RIFM report number 1802, August 13, unpublished.
HRIPT Human Patch Test Studies
5 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HRIPT | 99 | 0 | 23622 | 23622 | non-sensitizer |
| HMT | - | 0 | 2592 | - | - |
| HRIPT | - | 0 | 1033.34 | - | - |
| HRIPT | - | 0 | 23622.05 | - | - |
| HRIPT | - | 0 | 25984.25 | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for 2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol.
Regulatory Flags
fragrance-component
epa_safer_alternative
ifra_fragrance
Known Synonyms
Myrcenol, dihydro
7-Octen-2-ol, 2-methyl-6-methylene-, dihydro deriv.
EINECS 258-432-2
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
SCIL (9/2019)
consumer_product
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol allowed in the EU?
2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol do in cosmetics?
2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 53219-21-9.
Is 2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol used outside cosmetics?
2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 2-Ethyl-2-(3-Methylbut-2-Enyl)Hex-3-Enol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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