3-Nitro-4-Aminophenoxyethanol

CAS Number
50982-74-6 (tentative โ€” verify against CosIng; structurally: 2-(4-amino-3-nitrophenoxy)ethanol)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Reviewed within CIR assessments of nitro-amino phenol hair dyes; permitted with precautions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Nitro-amino compound with potential for nitrosamine formation if combined with nitrosating agents; must comply with secondary amine restrictions and avoid use in products containing nitrosating substances.

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Concern Level: High

Frequently Asked Questions

Is 3-Nitro-4-Aminophenoxyethanol safe in cosmetics?

Nitro-amino compound with potential for nitrosamine formation if combined with nitrosating agents; must comply with secondary amine restrictions and avoid use in products containing nitrosating substances. The EU classifies 3-Nitro-4-Aminophenoxyethanol as "prohibited". Safety rating: MODERATE.

Is 3-Nitro-4-Aminophenoxyethanol allowed in the EU?

3-Nitro-4-Aminophenoxyethanol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What is the Margin of Safety for 3-Nitro-4-Aminophenoxyethanol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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