3-Tert-Butyl-2-Methoxypyrazine

INCI: 3-TERT-BUTYL-2-METHOXYPYRAZINE

CAS Number
24168-70-5
Function
Fragrance with extremely potent green bell pepper aroma and ultra-low odor threshold of 1-2 ppt in water
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA GRAS; no specific FDA cosmetic restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Extremely potent fragrance ingredient with ultra-low odor threshold (1-2 ppt); precise dosing is critical to avoid profile domination by trace amounts, though GRAS status and low absorption profile support safety at appropriate use levels.

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is 3-Tert-Butyl-2-Methoxypyrazine safe in cosmetics?

Extremely potent fragrance ingredient with ultra-low odor threshold (1-2 ppt); precise dosing is critical to avoid profile domination by trace amounts, though GRAS status and low absorption profile support safety at appropriate use levels. The EU classifies 3-Tert-Butyl-2-Methoxypyrazine as "permitted". Safety rating: GOOD.

Is 3-Tert-Butyl-2-Methoxypyrazine allowed in the EU?

3-Tert-Butyl-2-Methoxypyrazine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 3-Tert-Butyl-2-Methoxypyrazine do in cosmetics?

3-Tert-Butyl-2-Methoxypyrazine functions as: Fragrance with extremely potent green bell pepper aroma and ultra-low odor threshold of 1-2 ppt in water. It is classified as a cosmetic ingredient in our database. CAS number: 24168-70-5.

What is the Margin of Safety for 3-Tert-Butyl-2-Methoxypyrazine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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