3,4-Dimethylcyclopentane-1,2-Dione
INCI: 3,4-DIMETHYLCYCLOPENTANE-1,2-DIONE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for 3,4-Dimethylcyclopentane-1,2-Dione. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Alpha-diketone with butterscotch-type fragrance note; inhalation hazard risk primarily associated with diacetyl but structural class warrants caution in sprayable or aerosolized products. Verify IFRA restrictions for intended use category.
Regulatory Flags
Frequently Asked Questions
Is 3,4-Dimethylcyclopentane-1,2-Dione safe in cosmetics?
Alpha-diketone with butterscotch-type fragrance note; inhalation hazard risk primarily associated with diacetyl but structural class warrants caution in sprayable or aerosolized products. Verify IFRA restrictions for intended use category. The EU classifies 3,4-Dimethylcyclopentane-1,2-Dione as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is 3,4-Dimethylcyclopentane-1,2-Dione allowed in the EU?
3,4-Dimethylcyclopentane-1,2-Dione EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 3,4-Dimethylcyclopentane-1,2-Dione do in cosmetics?
3,4-Dimethylcyclopentane-1,2-Dione functions as: Perfuming / flavoring (alpha-diketone, butterscotch-type note). It is classified as a cosmetic ingredient in our database. CAS number: 13494-07-0.
What is the Margin of Safety for 3,4-Dimethylcyclopentane-1,2-Dione?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 3,4-Dimethylcyclopentane-1,2-Dione?
The NOAEL (No Observed Adverse Effect Level) for 3,4-Dimethylcyclopentane-1,2-Dione is 500 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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