Is 3,4-Diaminobenzoic Acid safe in cosmetics?
3,4-Diaminobenzoic Acid has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Poor
Cosmetic Ingredient
3,4-Diaminobenzoic Acid
Also known as: EINECS 210-577-2, UNII-2H2G880K12
INCI: 3,4-DIAMINOBENZOIC ACID
3,4-Diaminobenzoic Acid (CAS 619-05-6) is a cosmetic cosmetic ingredient functioning as Hair dye precursor (oxidative). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 619-05-6 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
3,4-Diaminobenzoic Acid is prohibited in EU cosmetics but has active industrial GHS classifications.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word
Function
Hair dye precursor (oxidative)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
3,4-diaminobenzoic acid
InChIKey
HEMGYNNCNNODNX-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not specifically prohibited by FDA; no 21 CFR restriction identified
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 3,4-Diaminobenzoic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1229
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 3,4-Diaminobenzoic Acid.
Regulatory Flags
potential-allergen
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
EINECS 210-577-2
UNII-2H2G880K12
Chemical Function
Dye
Regulatory Lists
banned; Europe; Personal care
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3305820
Frequently Asked Questions
Is 3,4-Diaminobenzoic Acid allowed in the EU?
3,4-Diaminobenzoic Acid EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 3,4-Diaminobenzoic Acid do in cosmetics?
3,4-Diaminobenzoic Acid functions as: Hair dye precursor (oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 619-05-6.
Is 3,4-Diaminobenzoic Acid used outside cosmetics?
3,4-Diaminobenzoic Acid also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 3,4-Diaminobenzoic Acid have different safety status in cosmetics vs industrial chemicals?
3,4-Diaminobenzoic Acid is prohibited in EU cosmetics but has active industrial GHS classifications.
Compliance Tools
Check 3,4-Diaminobenzoic Acid compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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