4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate)
INCI: 4-FORMYL-2-METHOXYPHENYL ISOBUTYRATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for 4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
No significant safety concerns at typical fragrance concentrations.
Regulatory Flags
Frequently Asked Questions
Is 4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate) safe in cosmetics?
No significant safety concerns at typical fragrance concentrations. The EU classifies 4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate) as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is 4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate) allowed in the EU?
4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate) do in cosmetics?
4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate) functions as: Fragrance with sweet/vanilla olfactory profile. It is classified as a cosmetic ingredient in our database. CAS number: 20665-85-4.
What is the Margin of Safety for 4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate)?
The NOAEL (No Observed Adverse Effect Level) for 4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate) is 1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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