Also known as: Quinolinium, 4-formyl-1-methyl-, 4-methylbenzenesulfonate (1:1)
INCI: 4-FORMYL-1-METHYLQUINOLINIUM-P-TOLUENESULFONATE
4-Formyl-1-Methylquinolinium-P-Toluenesulfonate (CAS 223398-02-5) is a cosmetic cosmetic ingredient functioning as Hair dyeing. Reported NOAEL =0.009 mg/kg bw/d in rat (SCCS Opinion); EU Regulation 1223/2009 status: prohibited, max 2.5%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 223398-02-5 →
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Margin of Safety, dermal absorption, and sensitization profile summaries for 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate.
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10 study endpoints found for 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =0.009 mg/kg bw/d | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.009 mg/kg bw/d | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.009 mg/kg bw/d | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.009 mg/kg bw/d | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.0297 mg/kg bw/d | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.0297 mg/kg bw/d | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.0297 mg/kg bw/d | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.0297 mg/kg bw/d | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =100 mg/kg bw | oral | - | NOAEL study | SCCS Opinion |
| NOAEL | =100 mg/kg bw/d | oral | rat | dermal absorption | SCCS Opinion |
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Preliminary editorial summary for 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate — not a computed safety verdict. See the sourced toxicological data above.
Public NOAEL study rows linked to 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate by CAS number or substance name.
Units vary across source rows: mg/kg bw/d, mg/kg bw, mg/kg bw/day
4-Formyl-1-Methylquinolinium-P-Toluenesulfonate has a safety rating of "GOOD" in our database. EU status: prohibited. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
4-Formyl-1-Methylquinolinium-P-Toluenesulfonate EU regulatory status: prohibited. Maximum allowed concentration: 2.5%. This is based on EU Regulation 1223/2009 and its amendments.
4-Formyl-1-Methylquinolinium-P-Toluenesulfonate functions as: Hair dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 223398-02-5.
The NOAEL (No Observed Adverse Effect Level) for 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate is =0.009 mg/kg bw/d based on a dermal absorption study via oral route in rat. A total of 10 study endpoints are available. Source: SCCS Opinion.
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