4-Formyl-1-Methylquinolinium-P-Toluenesulfonate
INCI: 4-FORMYL-1-METHYLQUINOLINIUM-P-TOLUENESULFONATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 100 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| LOAEL | 316 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
Expert Verdict
Prohibited in EU; must not exceed 2.5% concentration. Permitted in US under coal-tar hair dye exemption; use only in combination with or without H₂O₂ on scalp.
Regulatory Flags
Frequently Asked Questions
Is 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate safe in cosmetics?
Prohibited in EU; must not exceed 2.5% concentration. Permitted in US under coal-tar hair dye exemption; use only in combination with or without H₂O₂ on scalp. The EU classifies 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate as "prohibited". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.
Is 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate allowed in the EU?
4-Formyl-1-Methylquinolinium-P-Toluenesulfonate EU regulatory status: prohibited. Maximum allowed concentration: 2.5%. This is based on EU Regulation 1223/2009 and its amendments.
What does 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate do in cosmetics?
4-Formyl-1-Methylquinolinium-P-Toluenesulfonate functions as: Hair dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 223398-02-5.
What is the Margin of Safety for 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate?
The NOAEL (No Observed Adverse Effect Level) for 4-Formyl-1-Methylquinolinium-P-Toluenesulfonate is 1000 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 3 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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