4-Methylpentan-2-Ol (MIBC)
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for 4-Methylpentan-2-Ol (MIBC). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 30 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Skin and eye irritant at higher concentrations; respiratory irritant. Typically used at very low concentrations in cosmetics.
Regulatory Flags
Frequently Asked Questions
Is 4-Methylpentan-2-Ol (MIBC) safe in cosmetics?
Skin and eye irritant at higher concentrations; respiratory irritant. Typically used at very low concentrations in cosmetics. The EU classifies 4-Methylpentan-2-Ol (MIBC) as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is 4-Methylpentan-2-Ol (MIBC) allowed in the EU?
4-Methylpentan-2-Ol (MIBC) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 4-Methylpentan-2-Ol (MIBC) do in cosmetics?
4-Methylpentan-2-Ol (MIBC) functions as: Chemical reaction regulator; Flavouring and nutrient; Fragrance; Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 108-11-2.
What is the Margin of Safety for 4-Methylpentan-2-Ol (MIBC)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 4-Methylpentan-2-Ol (MIBC)?
The NOAEL (No Observed Adverse Effect Level) for 4-Methylpentan-2-Ol (MIBC) is 30 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
Check 4-Methylpentan-2-Ol (MIBC) compliance across multiple jurisdictions:
Related Ingredients
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