4-Nitro-O-Phenylenediamine Dihydrochloride

INCI: 4-NITRO-O-PHENYLENEDIAMINE DIHYDROCHLORIDE

CAS Number
63411-72-3
Function
Hair dye (salt form)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Same framework as parent compound; CIR conclusion extends to salt forms

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Salt form subject to same Annex III restrictions and labeling requirements as parent compound, with concentration limits referring to free base equivalent.

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Concern Level: Moderate

Frequently Asked Questions

Is 4-Nitro-O-Phenylenediamine Dihydrochloride safe in cosmetics?

Salt form subject to same Annex III restrictions and labeling requirements as parent compound, with concentration limits referring to free base equivalent. The EU classifies 4-Nitro-O-Phenylenediamine Dihydrochloride as "restricted". Safety rating: MODERATE.

Is 4-Nitro-O-Phenylenediamine Dihydrochloride allowed in the EU?

4-Nitro-O-Phenylenediamine Dihydrochloride EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does 4-Nitro-O-Phenylenediamine Dihydrochloride do in cosmetics?

4-Nitro-O-Phenylenediamine Dihydrochloride functions as: Hair dye (salt form). It is classified as a cosmetic ingredient in our database. CAS number: 63411-72-3.

What is the Margin of Safety for 4-Nitro-O-Phenylenediamine Dihydrochloride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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