Good Cosmetic Ingredient NOAEL Data

5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE

CAS Number
698-10-2
Function
Perfuming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

2 study endpoints found for 5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1.3 mg/kg bw/day oral rat Subchronic COSMOS_DB
dose_tested 1.3 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted fragrance needs-enrichment ifra_fragrance fda_food_additive

Frequently Asked Questions

Is 5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE safe in cosmetics?

5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions. The EU classifies 5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE as "Permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is 5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE allowed in the EU?

5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE do in cosmetics?

5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 698-10-2.

What is the NOAEL for 5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE?

The NOAEL (No Observed Adverse Effect Level) for 5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE is 1.3 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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