5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone)
INCI: 5-ETHYL-3-HYDROXY-4-METHYLFURAN-2(5H)-ONE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1.3 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 1.3 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Limited dedicated cosmetic safety data for this specific CAS - safety extrapolated from related furanone isomers; also used in food/flavor applications
Regulatory Flags
Frequently Asked Questions
Is 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone) safe in cosmetics?
Limited dedicated cosmetic safety data for this specific CAS - safety extrapolated from related furanone isomers; also used in food/flavor applications The EU classifies 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone) as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone) allowed in the EU?
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone) do in cosmetics?
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone) functions as: Perfuming, skin conditioning; sweet caramel-like character. It is classified as a cosmetic ingredient in our database. CAS number: 698-10-2.
What is the Margin of Safety for 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone)?
The NOAEL (No Observed Adverse Effect Level) for 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (Emoxyfurone) is 1.3 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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