Is 6-Aminocaproic Acid safe in cosmetics?
6-Aminocaproic Acid has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: restricted.
Moderate
Cosmetic Ingredient
6-Aminocaproic Acid
Also known as: Hexanoic acid, 6-amino-, BRN 0906872, Capralense, Eaca kabi, EINECS 200-469-3 (+14 more)
INCI: 6-AMINOCAPROIC ACID
6-Aminocaproic Acid (CAS 60-32-2) is a cosmetic cosmetic ingredient functioning as Pharmaceutical antifibrinolytic agent. No cosmetic function. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 60-32-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
6-Aminocaproic Acid is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H335).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Pharmaceutical antifibrinolytic agent. No cosmetic function.
Safety Rating
MODERATE
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
FDA-approved pharmaceutical marketed as Amicar. Not approved for cosmetic use. Classified as a drug, not a cosmetic ingredient.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 6-Aminocaproic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 7
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 7
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (3)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| ASEAN | banned | - | All cosmetic products prohibited |
| KR | prohibited | - | - |
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
No specific technical function
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 6-Aminocaproic Acid.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
Hexanoic acid, 6-amino-
BRN 0906872
Capralense
Eaca kabi
EINECS 200-469-3
NSC-26154
omega-Aminocaproic acid
Epsilon-aminocapronzuur
Aminocaproic
Aminocaproic acid in plastic container
Kyselina omega-aminokapronova
UNII-U6F3787206
Epsilon Aminocaproic Acid
6-Amino-Hexanoate
6-Amino-Hexanoic acid
6-Amino-N-hexanoate
6-Aminocaproate
6-Aminohexanoate
Ahx
Chemical Function
No specific technical function
Regulatory Lists
pharmaceutical
pharmaceutical
Canada; pharmaceutical
Canada; pharmaceutical
banned; Europe; Personal care
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
AMINOCAPROIC ACID
ChEMBL ID
CHEMBL1046
Max Phase
4
Adverse Event Associations
220
Frequently Asked Questions
Is 6-Aminocaproic Acid allowed in the EU?
6-Aminocaproic Acid EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 6-Aminocaproic Acid do in cosmetics?
6-Aminocaproic Acid functions as: Pharmaceutical antifibrinolytic agent. No cosmetic function.. It is classified as a cosmetic ingredient in our database. CAS number: 60-32-2.
Is 6-Aminocaproic Acid used outside cosmetics?
6-Aminocaproic Acid also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 6-Aminocaproic Acid have different safety status in cosmetics vs industrial chemicals?
6-Aminocaproic Acid is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H335).
Compliance Tools
Check 6-Aminocaproic Acid compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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