Is 1-METHYLHYDANTOIN-2-IMIDE safe in cosmetics?
1-METHYLHYDANTOIN-2-IMIDE has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
1-METHYLHYDANTOIN-2-IMIDE
Also known as: Creatinine,heated, EINECS 200-466-7, UNII-AYI8EX34EU, 2-amino-1-methyl-5H-imidazol-4-one, Creatine anhydride (+2 more)
1-METHYLHYDANTOIN-2-IMIDE (CAS 60-27-5) is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 60-27-5 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-amino-3-methyl-4H-imidazol-5-one
InChIKey
DDRJAANPRJIHGJ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for 1-METHYLHYDANTOIN-2-IMIDE.
Regulatory Flags
cosing-sourced
eu-permitted
skin-conditioning
needs-enrichment
Known Synonyms
Creatinine,heated
EINECS 200-466-7
UNII-AYI8EX34EU
2-amino-1-methyl-5H-imidazol-4-one
Creatine anhydride
Kreatinin
creatinina
Chemical Function
Softener and conditioner
Regulatory Lists
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
CREATININE
ChEMBL ID
CHEMBL65567
Max Phase
3
Adverse Event Associations
41
Frequently Asked Questions
Is 1-METHYLHYDANTOIN-2-IMIDE allowed in the EU?
1-METHYLHYDANTOIN-2-IMIDE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 1-METHYLHYDANTOIN-2-IMIDE do in cosmetics?
1-METHYLHYDANTOIN-2-IMIDE functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 60-27-5.
Is 1-METHYLHYDANTOIN-2-IMIDE used outside cosmetics?
1-METHYLHYDANTOIN-2-IMIDE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 1-METHYLHYDANTOIN-2-IMIDE compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
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ADENOSINE CYCLIC PHOSPHATE
Good
Chemical family
Skin Conditioning
EDTA
Good
Chemical family
Chelating
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