Poor Cosmetic Ingredient GHS Classified

Acrolein

INCI: ACROLEIN

CAS Number
107-02-8
Function
No approved cosmetic function — it is an industrial chemical (2-propenal)
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status prohibited
US Notes Not approved for cosmetic use; classified as highly toxic by EPA. Severe irritant and sensitizer

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
DANGER
Pictograms
flam;flame; corr; skull;toxic; enviro;aqua
Hazard Statements
Extremely flammable liquid and vapour Causes severe skin burns and eye damage Fatal if swallowed or in contact with skin Toxic if inhaled May cause cancer May cause damage to upper respiratory tract through prolonged or repeated exposure Very toxic to aquatic life
Short-term Exposure Effects
Lachrymation. The vapour is severely irritating to the respiratory tract. The substance is corrosive to the eyes and skin. Inhalation of high concentrations may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated.
Long-term Exposure Effects
The substance may have effects on the respiratory tract. This substance is probably carcinogenic to humans.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. Serious local effects by all routes of exposure.

Expert Verdict

Acrolein is a Category 2 carcinogen and Category 1 acute toxin with mutagenicity concerns. This substance must never appear in a cosmetic formula. If detected as an impurity from degradation, it should be controlled to undetectable levels.

⚠️
Concern Level: High

Regulatory Flags

fda_food_additive

Frequently Asked Questions

Is Acrolein safe in cosmetics?

Acrolein is a Category 2 carcinogen and Category 1 acute toxin with mutagenicity concerns. This substance must never appear in a cosmetic formula. If detected as an impurity from degradation, it should be controlled to undetectable levels. The EU classifies Acrolein as "prohibited". Safety rating: POOR.

Is Acrolein allowed in the EU?

Acrolein EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Acrolein do in cosmetics?

Acrolein functions as: No approved cosmetic function — it is an industrial chemical (2-propenal). It is classified as a cosmetic ingredient in our database. CAS number: 107-02-8.

What is the Margin of Safety for Acrolein?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Is Acrolein classified as hazardous under GHS?

Acrolein carries a GHS signal word of "DANGER". Hazard statements: Extremely flammable liquid and vapour Causes severe skin burns and eye damage Fatal if swallowed or in contact with skin Toxic if inhaled May cause cancer May cause damage to upper respiratory tract through prolonged or repeated exposure Very toxic to aquatic life. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.

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