Is Allantoin Biotin safe in cosmetics?
Allantoin Biotin has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Allantoin Biotin
INCI: ALLANTOIN BIOTIN
Allantoin Biotin (CAS 4492-73-3) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Skin Protecting, Soothing. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 4492-73-3 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Skin Protecting, Soothing
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid;(2,5-dioxoimidazolidin-4-yl)urea
InChIKey
DCWBLFMYZJBXPI-UFLZEWODSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR-reviewed: Safe as used — included in the same 2010 CIR allantoin complex report; biotin independently reviewed safe by CIR (≤0.6%)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Allantoin Biotin.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Pharmaceutical
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Allantoin Biotin.
Chemical Function
Humectant
Softener and conditioner
Pharmaceutical
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Frequently Asked Questions
Is Allantoin Biotin allowed in the EU?
Allantoin Biotin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Allantoin Biotin do in cosmetics?
Allantoin Biotin functions as: Skin Conditioning, Skin Protecting, Soothing. It is classified as a cosmetic ingredient in our database. CAS number: 4492-73-3.
Compliance Tools
Check Allantoin Biotin compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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