Allantoin Biotin

INCI: ALLANTOIN BIOTIN

CAS Number
4492-73-3
Function
Skin Conditioning, Skin Protecting, Soothing
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR-reviewed: Safe as used โ€” included in the same 2010 CIR allantoin complex report; biotin independently reviewed safe by CIR (โ‰ค0.6%)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Minimal risk. Both allantoin and biotin have robust safety profiles and are permitted for cosmetic use.

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Concern Level: Low

Frequently Asked Questions

Is Allantoin Biotin safe in cosmetics?

Minimal risk. Both allantoin and biotin have robust safety profiles and are permitted for cosmetic use. The EU classifies Allantoin Biotin as "permitted". Safety rating: EXCELLENT.

Is Allantoin Biotin allowed in the EU?

Allantoin Biotin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Allantoin Biotin do in cosmetics?

Allantoin Biotin functions as: Skin Conditioning, Skin Protecting, Soothing. It is classified as a cosmetic ingredient in our database. CAS number: 4492-73-3.

What is the Margin of Safety for Allantoin Biotin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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