Is Allyl Cyclohexyloxyacetate safe in cosmetics?
Allyl Cyclohexyloxyacetate has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted. 4 toxicological study endpoint(s) are available in our database.
Allyl Cyclohexyloxyacetate
Also known as: Acetic acid, (cyclohexyloxy)-, 2-propenyl ester, Acetic acid, 2-(cyclohexyloxy)-, 2-propen-1-yl ester, Allyl (cyclohexyloxy)acetate, EINECS 272-657-3, Cyclogalbanate (+1 more)
INCI: ALLYL CYCLOHEXYLOXYACETATE
Allyl Cyclohexyloxyacetate (CAS 68901-15-5) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming agent). Reported NOAEL =16.1 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 68901-15-5 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance (perfuming agent)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
prop-2-enyl 2-cyclohexyloxyacetate
InChIKey
MBUYSYKXSMTIPP-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Permitted in cosmetics; no specific FDA restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Allyl Cyclohexyloxyacetate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Allyl Cyclohexyloxyacetate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =16.1 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
| NOAEL | =32.2 mg/kg bw/day | oral | Rat | short-term | ToxValDB_ECHA_IUCLID |
| NOAEL | =32.8 mg/kg bw/day | oral | Rat | short-term | ToxValDB_ECHA_IUCLID |
| NOAEL | =60 mg/kg bw/day | oral | Rat | developmental | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
BRIN Brazil/India Cosmetics
India: Restricted
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
Consumer Product Chemical
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Allyl Cyclohexyloxyacetate.
Regulatory Flags
fragrance-component
ifra_fragrance
eu_cosing_listed
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Allyl Cyclohexyloxyacetate by CAS number or substance name.
Studies
4
Lowest NOAEL
16.1 mg/kg bw/day
Highest NOAEL
60 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Acetic acid, (cyclohexyloxy)-, 2-propenyl ester
Acetic acid, 2-(cyclohexyloxy)-, 2-propen-1-yl ester
Allyl (cyclohexyloxy)acetate
EINECS 272-657-3
Cyclogalbanate
Galbanum oxyacetate
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
consumer_product
Europe; Personal care; restricted
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Allyl Cyclohexyloxyacetate allowed in the EU?
Allyl Cyclohexyloxyacetate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Allyl Cyclohexyloxyacetate do in cosmetics?
Allyl Cyclohexyloxyacetate functions as: Fragrance (perfuming agent). It is classified as a cosmetic ingredient in our database. CAS number: 68901-15-5.
What is the NOAEL for Allyl Cyclohexyloxyacetate?
The NOAEL (No Observed Adverse Effect Level) for Allyl Cyclohexyloxyacetate is =16.1 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 4 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is Allyl Cyclohexyloxyacetate used outside cosmetics?
Allyl Cyclohexyloxyacetate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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