Aminopropyl Dihydrogen Phosphate

INCI: AMINOPROPYL DIHYDROGEN PHOSPHATE

CAS Number
13598-07-7 (3-aminopropyl dihydrogen phosphate)
Function
Buffering agent; skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No CIR review; not specifically restricted by FDA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Data gap โ€” no CIR or SCCS opinion; primary amine functionality means N-nitrosamine formation risk if combined with nitrosating agents; formulators should obtain supplier safety dossier and consider commissioning HRIPT if used at significant concentrations

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Concern Level: Moderate

Frequently Asked Questions

Is Aminopropyl Dihydrogen Phosphate safe in cosmetics?

Data gap โ€” no CIR or SCCS opinion; primary amine functionality means N-nitrosamine formation risk if combined with nitrosating agents; formulators should obtain supplier safety dossier and consider commissioning HRIPT if used at significant concentrations The EU classifies Aminopropyl Dihydrogen Phosphate as "permitted". Safety rating: MODERATE.

Is Aminopropyl Dihydrogen Phosphate allowed in the EU?

Aminopropyl Dihydrogen Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aminopropyl Dihydrogen Phosphate do in cosmetics?

Aminopropyl Dihydrogen Phosphate functions as: Buffering agent; skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 13598-07-7 (3-aminopropyl dihydrogen phosphate).

What is the Margin of Safety for Aminopropyl Dihydrogen Phosphate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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