AMP-C8-18 Perfluoroalkylethyl Phosphate

INCI: AMP-C8-18 PERFLUOROALKYLETHYL PHOSPHATE

CAS Number
65530-64-5
Function
Emulsion stabilising, solvent, surfactant-cleansing
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted but under active FDA review. MoCRA mandated FDA to assess PFAS safety in cosmetics, with a report due December 2025.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PFAS (per-/polyfluoroalkyl substance) with persistent, bioaccumulative, and potentially toxic properties. Listed on Walgreens Boots Alliance Chemical Action List and banned by H&M Group. FDA identified it as a PFAS in their 2025 report. Environmental persistence and multiple jurisdictions moving toward PFAS bans in cosmetics; ECHA PFAS restriction proposal may eliminate this ingredient from the EU market entirely.

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Concern Level: High

Frequently Asked Questions

Is AMP-C8-18 Perfluoroalkylethyl Phosphate safe in cosmetics?

PFAS (per-/polyfluoroalkyl substance) with persistent, bioaccumulative, and potentially toxic properties. Listed on Walgreens Boots Alliance Chemical Action List and banned by H&M Group. FDA identified it as a PFAS in their 2025 report. Environmental persistence and multiple jurisdictions moving toward PFAS bans in cosmetics; ECHA PFAS restriction proposal may eliminate this ingredient from the EU market entirely. The EU classifies AMP-C8-18 Perfluoroalkylethyl Phosphate as "prohibited". Safety rating: POOR.

Is AMP-C8-18 Perfluoroalkylethyl Phosphate allowed in the EU?

AMP-C8-18 Perfluoroalkylethyl Phosphate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does AMP-C8-18 Perfluoroalkylethyl Phosphate do in cosmetics?

AMP-C8-18 Perfluoroalkylethyl Phosphate functions as: Emulsion stabilising, solvent, surfactant-cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 65530-64-5.

What is the Margin of Safety for AMP-C8-18 Perfluoroalkylethyl Phosphate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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