Is Arginine PCA safe in cosmetics?
Arginine PCA has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Arginine PCA
INCI: ARGININE PCA
Arginine PCA (CAS 56265-06-6 / 64855-91-0) is a cosmetic cosmetic ingredient functioning as Humectant, Skin Conditioning, Hair Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 56265-06-6 / 64855-91-0 →
Auto-generated CPSR Part A draft with source citations
Function
Humectant, Skin Conditioning, Hair Conditioning
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR: Safe as used (covered under amino acid and PCA salt reviews)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Arginine PCA.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
amino_acid
{"cas_number": "56265-06-6", "ingredient_class": "amino_acid", "source_origin": "synthetic", "molecular_weight_range_Da": "303", "amino_acid_composition_key": "arginine_PCA", "charge_at_pH_5_5": "cationic", "water_solubility": "soluble", "oil_solubility": "insoluble", "film_forming_ability": "good", "moisture_binding_capacity": "excellent", "NMF_component": "yes", "skin_penetration_depth": "epider…
ph_stability
{"optimal_ph_min": "5.0", "optimal_ph_max": "8.0", "stable_ph_min": "4.5", "stable_ph_max": "9.0", "degrades_above_ph": "10.0", "degrades_below_ph": "4.0", "ph_dependent_function": "Amino acid derivative", "formulation_note": "Humectant and pH adjuster", "source": "Formulation literature"}
Expert Verdict
Expert safety assessment and concern-level summary for Arginine PCA.
Frequently Asked Questions
Is Arginine PCA allowed in the EU?
Arginine PCA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Arginine PCA do in cosmetics?
Arginine PCA functions as: Humectant, Skin Conditioning, Hair Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 56265-06-6 / 64855-91-0.
Compliance Tools
Check Arginine PCA compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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