Azadirachta Indica Bark/Seed Extract

INCI: AZADIRACHTA INDICA BARK/SEED EXTRACT

CAS Number
84696-25-3
Function
(No specific function assigned in CosIng - historically used as skin conditioning)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no explicit prohibition under US regulations; however, limited commercial use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

The combined bark/seed extract contains high levels of azadirachtin and other limonoids from the seed fraction; reproductive toxicity concerns and potential endocrine-disrupting properties prompted EU prohibition. Plant origin; the prohibition specifically targets the combined bark/seed extract - note that pure bark extract (ingredient \#8 above) is treated differently under EU regulation

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Azadirachta Indica Bark/Seed Extract safe in cosmetics?

The combined bark/seed extract contains high levels of azadirachtin and other limonoids from the seed fraction; reproductive toxicity concerns and potential endocrine-disrupting properties prompted EU prohibition. Plant origin; the prohibition specifically targets the combined bark/seed extract - note that pure bark extract (ingredient \#8 above) is treated differently under EU regulation The EU classifies Azadirachta Indica Bark/Seed Extract as "prohibited". Safety rating: MODERATE.

Is Azadirachta Indica Bark/Seed Extract allowed in the EU?

Azadirachta Indica Bark/Seed Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Azadirachta Indica Bark/Seed Extract do in cosmetics?

Azadirachta Indica Bark/Seed Extract functions as: (No specific function assigned in CosIng - historically used as skin conditioning). It is classified as a cosmetic ingredient in our database. CAS number: 84696-25-3.

What is the Margin of Safety for Azadirachta Indica Bark/Seed Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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