Is Azadirachta Indica Seed Extract safe in cosmetics?
Azadirachta Indica Seed Extract has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
MODERATE
Cosmetic Ingredient
Azadirachta Indica Seed Extract
INCI: AZADIRACHTA INDICA SEED EXTRACT
Azadirachta Indica Seed Extract (CAS 84696-25-3) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 84696-25-3 →
Function
Skin conditioning
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Allowed - not specifically prohibited or restricted; neem-derived ingredients appear in US market products
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Azadirachta Indica Seed Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Hazard Class and Category
Aquatic Chronic 3
Hazard Statements
- H412 Harmful to aquatic life with long lasting effects
Inserted via ATP: ATP15
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1716
(EU) 2023/1490
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Editorial summary
Preliminary editorial summary for Azadirachta Indica Seed Extract — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
plant-extract
potential-allergen
Chemical Function
Softener and conditioner
Regulatory Lists
active_ingredient
Europe
Pesticides
Frequently Asked Questions
Is Azadirachta Indica Seed Extract allowed in the EU?
Azadirachta Indica Seed Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Azadirachta Indica Seed Extract do in cosmetics?
Azadirachta Indica Seed Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84696-25-3.
Compliance Tools
Check Azadirachta Indica Seed Extract compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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