Azadirachta Indica Seed Extract

INCI: AZADIRACHTA INDICA SEED EXTRACT

CAS Number
84696-25-3
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not specifically prohibited or restricted; neem-derived ingredients appear in US market products

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains azadirachtin and other limonoids with known reproductive toxicity potential, which drove the EU prohibition. Sensitization possible in susceptible individuals. Derived from neem tree (Meliaceae family) seeds via solvent extraction; historically valued for antibacterial, antifungal, and anti-inflammatory activity

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Azadirachta Indica Seed Extract safe in cosmetics?

Contains azadirachtin and other limonoids with known reproductive toxicity potential, which drove the EU prohibition. Sensitization possible in susceptible individuals. Derived from neem tree (Meliaceae family) seeds via solvent extraction; historically valued for antibacterial, antifungal, and anti-inflammatory activity The EU classifies Azadirachta Indica Seed Extract as "prohibited". Safety rating: MODERATE.

Is Azadirachta Indica Seed Extract allowed in the EU?

Azadirachta Indica Seed Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Azadirachta Indica Seed Extract do in cosmetics?

Azadirachta Indica Seed Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84696-25-3.

What is the Margin of Safety for Azadirachta Indica Seed Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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