Is Benzophenone-5 safe in cosmetics?
Benzophenone-5 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Benzophenone-5
Also known as: Cyasorb UV 284, Uvistat 112, UNII-853Z42ZYAS
INCI: BENZOPHENONE-5
Benzophenone-5 (CAS 6628-37-1) is a cosmetic cosmetic ingredient functioning as UV filter, UV absorber, light stabilizer. EU Regulation 1223/2009 status: permitted, max 5%. Industrial safety data is also available in the chemical safety database.
Function
UV filter, UV absorber, light stabilizer
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
EU Max Conc.
5%
US US Status
permitted
US Notes
Not listed as OTC sunscreen active (BP-4 is, but BP-5 is not); CIR concluded safe (2021)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Benzophenone-5.
Calculate MoS for your specific formulation with the MoS Calculator.
Endocrine Disruptor Evidence (Expanded)
Cross-referenced EDC classifications, mechanism data, and dose-response evidence from EDLists, SIN List, and cosmetic-specific detail sources.
Suspected
Evidence: Limited
(2019)
Health effects: Yes
Affected pathways: Estrogenic
Regulatory framework: Cosmetics
Source list: II
Cosmetic-Specific Mechanism
Category: UV filter
Receptor targets: ERα, ERβ, AR
LOEC: 1 µM
EU status: restricted (max 5%, SCCS/1679/25 safe read-across BP-4)
agonist (ERα, ERβ); antagonist (AR)
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (2)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | permitted_uv_filter | 5 | All cosmetics |
| IN | permitted_uv_filter | 5.0 | sunscreen and other cosmetic products |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
UV stabilizer
Editorial summary
Preliminary editorial summary for Benzophenone-5 — not a computed safety verdict. See the sourced toxicological data above.
Known Synonyms
Cyasorb UV 284
Uvistat 112
UNII-853Z42ZYAS
Chemical Function
UV stabilizer
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Benzophenone-5 allowed in the EU?
Benzophenone-5 EU regulatory status: permitted. Maximum allowed concentration: 5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Benzophenone-5 do in cosmetics?
Benzophenone-5 functions as: UV filter, UV absorber, light stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 6628-37-1.
Compliance Tools
Check Benzophenone-5 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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