Is Triethoxycaprylylsilane safe in cosmetics?
Triethoxycaprylylsilane has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Triethoxycaprylylsilane
Also known as: EINECS 220-941-2, UNII-LDC331P08E
INCI: TRIETHOXYCAPRYLYLSILANE
Triethoxycaprylylsilane (CAS 2943-75-1) is a cosmetic cosmetic ingredient functioning as Binder, Surface Modifier, Skin Conditioning Agent (used to coat pigments and UV. NOAEL 250 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 2943-75-1 →
Auto-generated CPSR Part A draft with source citations
Function
Binder, Surface Modifier, Skin Conditioning Agent (used to coat pigments and UV filters)
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
triethoxy(octyl)silane
InChIKey
MSRJTTSHWYDFIU-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; CIR Expert Panel concluded safe as used in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Triethoxycaprylylsilane.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Triethoxycaprylylsilane across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
2 property records from structured ingredient metadata.
sensory
{"silky": "light", "smooth, glides easily": "smooth, water-repellent", "dry-touch, non-greasy": "protected, dry", "instant": "fast", "low": "low", "w/o": "w/o", "very-high": "high", "no": "yes", "yes": "yes", "1.40": "1.42", "transparent": "transparent", "colorless": "colorless", "excellent": "excellent", "light": "light", "synthetic": "synthetic"}
silicone
{"cas_number": "2943-75-1", "silicone_class": "organosilane", "molecular_weight_Da": "276.0", "viscosity_cSt": "liquid", "volatility": "non_volatile", "evaporation_rate_relative_to_D5": "0.05", "refractive_index": "1.418", "specific_gravity": "0.885", "flash_point_C": "78.0", "surface_tension_mN_m": "22.8", "spreading_coefficient": "3.4", "film_forming_ability": "good", "skin_feel": "powdery", "sl…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter
Binder
Chemical reaction regulator
Dispersing agent
Hardener
Processing aids not otherwise specified
Sealant (barrier)
Surface modifier
Thickening agent
Waterproofing agent
Expert Verdict
Expert safety assessment and concern-level summary for Triethoxycaprylylsilane.
Known Synonyms
EINECS 220-941-2
UNII-LDC331P08E
Chemical Function
Binder
Waterproofing agent
Sealant (barrier)
Regulatory Lists
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3185786
Frequently Asked Questions
Is Triethoxycaprylylsilane allowed in the EU?
Triethoxycaprylylsilane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Triethoxycaprylylsilane do in cosmetics?
Triethoxycaprylylsilane functions as: Binder, Surface Modifier, Skin Conditioning Agent (used to coat pigments and UV filters). It is classified as a cosmetic ingredient in our database. CAS number: 2943-75-1.
Is Triethoxycaprylylsilane used outside cosmetics?
Triethoxycaprylylsilane also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Triethoxycaprylylsilane compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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