Is Benzyl Nicotinate safe in cosmetics?
Benzyl Nicotinate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Benzyl Nicotinate
Also known as: 3-Pyridinecarboxylic acid, phenylmethyl ester, BRN 0159169, EINECS 202-332-3, Niacin benzyl ester, Pycaril (+11 more)
INCI: BENZYL NICOTINATE
Benzyl Nicotinate (CAS 94-44-0) is a cosmetic cosmetic ingredient functioning as Antistatic, Skin Conditioning, Rubefacient, Vasodilator. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 94-44-0 →
Auto-generated CPSR Part A draft with source citations
Function
Antistatic, Skin Conditioning, Rubefacient, Vasodilator
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
benzyl pyridine-3-carboxylate
InChIKey
KVYGGMBOZFWZBQ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No CIR review completed. Not on FDA prohibited/restricted list. Used in lip plumpers and topical vasodilator products. GHS07 classified (H315, H319). EWG score LOW across all concern categories with limited data availability.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Benzyl Nicotinate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Benzyl Nicotinate.
Regulatory Flags
skin-irritant
penetration-enhancer
vasodilator
rubefacient
limited-safety-data
no-cir-review
low-ewg-score
Known Synonyms
3-Pyridinecarboxylic acid, phenylmethyl ester
BRN 0159169
EINECS 202-332-3
Niacin benzyl ester
Pycaril
Pykaryl
Rubriment
Benzylis nicotinas
Nicotinsaeurebenzylester
Pyridin-3-carbonsaeurebenzylester
Estru benzylowego kwasu nikotynowego
UNII-S497LCF9C9
3-pyridinecarboxylic acid phenylmethyl ester
Nicotinic acid benzyl ester
benzyl pyridine-3-carboxylate
phenylmethyl 3-pyridinecarboxylate
Chemical Function
Anti-static agent
Softener and conditioner
Regulatory Lists
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BENZYL NICOTINATE
ChEMBL ID
CHEMBL209744
Max Phase
-1
Frequently Asked Questions
Is Benzyl Nicotinate allowed in the EU?
Benzyl Nicotinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Benzyl Nicotinate do in cosmetics?
Benzyl Nicotinate functions as: Antistatic, Skin Conditioning, Rubefacient, Vasodilator. It is classified as a cosmetic ingredient in our database. CAS number: 94-44-0.
Is Benzyl Nicotinate used outside cosmetics?
Benzyl Nicotinate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Benzyl Nicotinate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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