Benzyl Nicotinate

INCI: BENZYL NICOTINATE

CAS Number
94-44-0
Function
Antistatic, Skin Conditioning, Rubefacient, Vasodilator
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No CIR review completed. Not on FDA prohibited/restricted list. Used in lip plumpers and topical vasodilator products. GHS07 classified (H315, H319). EWG score LOW across all concern categories with limited data availability.

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Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Functionally effective vasodilator and skin conditioning agent used in lip plumpers and scalp tonics. Causes concentration-dependent skin irritation (H315), serious eye irritation (H319), and characteristic rubefacient flushing upon topical application. Acts as a penetration enhancer, potentially increasing systemic absorption of co-applied ingredients. No CIR assessment and limited published safety data. Not prohibited or restricted in EU or US. Acceptable at low use concentrations in rinse-off or limited-contact products with appropriate formulatory caution; warrants higher scrutiny in leave-on products applied over large surface areas.

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Concern Level: Moderate

Regulatory Flags

skin-irritant penetration-enhancer vasodilator rubefacient limited-safety-data no-cir-review low-ewg-score

Frequently Asked Questions

Is Benzyl Nicotinate safe in cosmetics?

Functionally effective vasodilator and skin conditioning agent used in lip plumpers and scalp tonics. Causes concentration-dependent skin irritation (H315), serious eye irritation (H319), and characteristic rubefacient flushing upon topical application. Acts as a penetration enhancer, potentially increasing systemic absorption of co-applied ingredients. No CIR assessment and limited published safety data. Not prohibited or restricted in EU or US. Acceptable at low use concentrations in rinse-off or limited-contact products with appropriate formulatory caution; warrants higher scrutiny in leave-on products applied over large surface areas. The EU classifies Benzyl Nicotinate as "permitted". Safety rating: MODERATE.

Is Benzyl Nicotinate allowed in the EU?

Benzyl Nicotinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Benzyl Nicotinate do in cosmetics?

Benzyl Nicotinate functions as: Antistatic, Skin Conditioning, Rubefacient, Vasodilator. It is classified as a cosmetic ingredient in our database. CAS number: 94-44-0.

What is the Margin of Safety for Benzyl Nicotinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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