Is Benzyl Tiglate safe in cosmetics?
Benzyl Tiglate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Benzyl Tiglate
Also known as: 2-Butenoic acid, 2-methyl-, phenylmethyl ester, (2E)-, 2-Butenoic acid, 2-methyl-, phenylmethyl ester, (E)-, Benzyl 2-methylcrotonate, Benzyl trans-2,3-dimethylacrylate, Benzyl trans-2-methyl-2-butenoate (+7 more)
INCI: BENZYL TIGLATE
Benzyl Tiglate (CAS 37526-88-8) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 37526-88-8 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically restricted; falls under general fragrance ingredient allowance. No FDA monograph.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Benzyl Tiglate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 6750 | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Benzyl Tiglate.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
2-Butenoic acid, 2-methyl-, phenylmethyl ester, (2E)-
2-Butenoic acid, 2-methyl-, phenylmethyl ester, (E)-
Benzyl 2-methylcrotonate
Benzyl trans-2,3-dimethylacrylate
Benzyl trans-2-methyl-2-butenoate
Benzyl trans-2-methylcrotonate
trans-2-Butenoic acid, 2-methyl-, phenylmethyl ester
EINECS 253-544-8
FEMA No. 3330
NSC 69098
Phenylmethyl 2-methyl-2-butenoate, (E)-
UNII-67UEP899RR
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3186295
Frequently Asked Questions
Is Benzyl Tiglate allowed in the EU?
Benzyl Tiglate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Benzyl Tiglate do in cosmetics?
Benzyl Tiglate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 37526-88-8.
Is Benzyl Tiglate used outside cosmetics?
Benzyl Tiglate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Benzyl Tiglate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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