Moderate Cosmetic Ingredient Sensitization Data

Benzylhemiformal

Also known as: Methanol, (phenylmethoxy)-, Methanol, 1-(phenylmethoxy)-, Benzyl hemiformal, EINECS 238-588-8, UNII-XDK482748R

INCI: BENZYLHEMIFORMAL

Benzylhemiformal (CAS 14548-60-8) is a cosmetic cosmetic ingredient functioning as Preservative (formaldehyde releaser). EU Regulation 1223/2009 status: restricted, max 0.15%. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 14548-60-8 →

Auto-generated CPSR Part A draft with source citations
Function
Preservative (formaldehyde releaser)
Safety Rating
MODERATE

Chemistry & Identifiers

Regulatory Status

EU EU Status restricted
EU Max Conc. 0.15%
US US Status permitted
US Notes Permitted; no specific concentration limit from FDA, but CIR has reviewed formaldehyde releasers collectively

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Benzylhemiformal.

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Benzylhemiformal based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
preservative
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
formaldehyde-releaser-group
Reaction Type
contact-dermatitis

Source: ESSCA 2019/20; IVDK; FDA

EU CosIng Annex Listing

European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.

Annex V — Permitted Preservatives
Product type: Rinse-off products
Max: 0.15%

Expanded Jurisdictional Detail

Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.

KR Korea MFDS Annex 2 (Restricted)
Category: Preservative. Max: 0.15% (rinse-off only). Leave-on prohibited
SA Saudi SFDA (V - Preservatives)
Product type: Rinse-off products. Max: 0.0015.
BRIN Brazil/India Cosmetics
Brazil: Permitted Preservative · max 0,15%
India: Permitted Preservative · max 0.0015
Additional Jurisdictional Restrictions (3)
Jurisdiction Status Max % Product Type
IN permitted_preservative 0.15 rinse-off products only
BR permitted_preservative 0.15 Prohibited in leave-on products
ASEAN permitted_preservative 0.15% Rinse-off products only

Additional Ingredient Properties

1 property record from structured ingredient metadata.

allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "preservative", "cross_reactivity_group": "formaldehyde-releaser-group", "patch_test_frequency_pct": "0.3", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "ESSCA 2019/20; IVDK; FDA"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Biocide Preservative
Regulatory List Membership (2)
EU Regulated in Personal Care EU CosIng Cosmetics Ingredient Database

Expert Verdict

Expert safety assessment and concern-level summary for Benzylhemiformal.

Regulatory Flags

preservative eu_cosing_listed

Known Synonyms

Methanol, (phenylmethoxy)- Methanol, 1-(phenylmethoxy)- Benzyl hemiformal EINECS 238-588-8 UNII-XDK482748R

Chemical Function

Preservative Biocide

Regulatory Lists

active_ingredient; Europe; Pesticides inert_ingredient; non_food_use; Pesticides Europe; Personal care

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Benzylhemiformal safe in cosmetics?

Benzylhemiformal has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.

Is Benzylhemiformal allowed in the EU?

Benzylhemiformal EU regulatory status: restricted. Maximum allowed concentration: 0.15%. This is based on EU Regulation 1223/2009 and its amendments.

What does Benzylhemiformal do in cosmetics?

Benzylhemiformal functions as: Preservative (formaldehyde releaser). It is classified as a cosmetic ingredient in our database. CAS number: 14548-60-8.

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