Moderate Cosmetic Ingredient Sensitization Data

Benzylhemiformal

INCI: BENZYLHEMIFORMAL

CAS Number
14548-60-8
Function
Preservative (formaldehyde releaser)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.15%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no specific concentration limit from FDA, but CIR has reviewed formaldehyde releasers collectively

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Benzylhemiformal based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
preservative
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
formaldehyde-releaser-group
Reaction Type
contact-dermatitis

Source: ESSCA 2019/20; IVDK; FDA

Expert Verdict

Formaldehyde releaser classified Carc. 1B (inhalation); spray/aerosol applications excluded. Mandatory formaldehyde labeling required above threshold. Not permitted in leave-on products in EU. Increasingly restricted by retailers and clean-beauty standards.

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Concern Level: High

Regulatory Flags

preservative eu_cosing_listed

Frequently Asked Questions

Is Benzylhemiformal safe in cosmetics?

Formaldehyde releaser classified Carc. 1B (inhalation); spray/aerosol applications excluded. Mandatory formaldehyde labeling required above threshold. Not permitted in leave-on products in EU. Increasingly restricted by retailers and clean-beauty standards. The EU classifies Benzylhemiformal as "restricted". Safety rating: MODERATE.

Is Benzylhemiformal allowed in the EU?

Benzylhemiformal EU regulatory status: restricted. Maximum allowed concentration: 0.15%. This is based on EU Regulation 1223/2009 and its amendments.

What does Benzylhemiformal do in cosmetics?

Benzylhemiformal functions as: Preservative (formaldehyde releaser). It is classified as a cosmetic ingredient in our database. CAS number: 14548-60-8.

What is the Margin of Safety for Benzylhemiformal?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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