Berberis Aquifolium Extract

INCI: BERBERIS AQUIFOLIUM EXTRACT

CAS Number
84696-12-8 (commonly listed)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated; permitted as botanical cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Berberine content must be quantified and specified on CoA. EFSA has flagged berberine-containing preparations for safety review. Potential phototoxicity of alkaloids โ€” photoirritation testing recommended.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Berberis Aquifolium Extract safe in cosmetics?

Berberine content must be quantified and specified on CoA. EFSA has flagged berberine-containing preparations for safety review. Potential phototoxicity of alkaloids โ€” photoirritation testing recommended. The EU classifies Berberis Aquifolium Extract as "restricted". Safety rating: MODERATE.

Is Berberis Aquifolium Extract allowed in the EU?

Berberis Aquifolium Extract EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Berberis Aquifolium Extract do in cosmetics?

Berberis Aquifolium Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84696-12-8 (commonly listed).

What is the Margin of Safety for Berberis Aquifolium Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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