Bisabolene

INCI: BISABOLENE

CAS Number
495-62-5
Function
Fragrance ingredient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes RIFM safety assessment completed โ€” safe as used at reported levels; evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, skin sensitization, phototoxicity, and environmental safety

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potential for autoxidation forming sensitizing hydroperoxides; fresh and properly stored material recommended.

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Concern Level: Low

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Bisabolene safe in cosmetics?

Potential for autoxidation forming sensitizing hydroperoxides; fresh and properly stored material recommended. The EU classifies Bisabolene as "permitted". Safety rating: GOOD.

Is Bisabolene allowed in the EU?

Bisabolene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bisabolene do in cosmetics?

Bisabolene functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 495-62-5.

What is the Margin of Safety for Bisabolene?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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