Butoxyethyl Acetate

INCI: BUTOXYETHYL ACETATE

CAS Number
112-07-2 (2-Butoxyethyl acetate; ethylene glycol butyl ether acetate)
Function
Solvent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Requires toxicological read-across from Butoxyethanol data

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Metabolic prodrug of Butoxyethanol โ€“ in vivo ester hydrolysis yields Butoxyethanol and acetic acid; CPSR must account for molar-equivalent systemic exposure to Butoxyethanol; Safety Assessor should apply read-across from Annex III Butoxyethanol data.

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Concern Level: Moderate

Frequently Asked Questions

Is Butoxyethyl Acetate safe in cosmetics?

Metabolic prodrug of Butoxyethanol โ€“ in vivo ester hydrolysis yields Butoxyethanol and acetic acid; CPSR must account for molar-equivalent systemic exposure to Butoxyethanol; Safety Assessor should apply read-across from Annex III Butoxyethanol data. The EU classifies Butoxyethyl Acetate as "restricted". Safety rating: MODERATE.

Is Butoxyethyl Acetate allowed in the EU?

Butoxyethyl Acetate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Butoxyethyl Acetate do in cosmetics?

Butoxyethyl Acetate functions as: Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 112-07-2 (2-Butoxyethyl acetate; ethylene glycol butyl ether acetate).

What is the Margin of Safety for Butoxyethyl Acetate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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