C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride

INCI: C4-18 PERFLUOROALKYLETHYL THIOHYDROXYPROPYLTRIMONIUM CHLORIDE

CAS Number
70983-60-7
Function
Hair Conditioning; Antimicrobial Enhancer
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Insufficient - no published MoS for cosmetic use; PFAS persistence and bioaccumulation make standard MoS methodology problematic

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PFAS ingredient with bioaccumulative and environmentally persistent properties; restricted by H&M Group RSL, Boots RSL, and numerous retailer restricted substance lists; facing imminent EU-wide PFAS restriction; no CIR review; unsuitable for new product development; strongly recommend substitution

โš ๏ธ
Concern Level: High

Frequently Asked Questions

Is C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride safe in cosmetics?

PFAS ingredient with bioaccumulative and environmentally persistent properties; restricted by H&M Group RSL, Boots RSL, and numerous retailer restricted substance lists; facing imminent EU-wide PFAS restriction; no CIR review; unsuitable for new product development; strongly recommend substitution The EU classifies C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride as "permitted". Safety rating: POOR.

Is C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride allowed in the EU?

C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride do in cosmetics?

C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride functions as: Hair Conditioning; Antimicrobial Enhancer. It is classified as a cosmetic ingredient in our database. CAS number: 70983-60-7.

What is the Margin of Safety for C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for C4-18 Perfluoroalkylethyl Thiohydroxypropyltrimonium Chloride in your formulation.