Moderate Cosmetic Ingredient NOAEL Data

Lauralkonium Chloride

INCI: LAURALKONIUM CHLORIDE

CAS Number
139-07-1
Function
Antistatic (reduces electrostatic charges in hair) and preservative (protects products from microbial spoilage)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 0.1%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed. CIR (Cosmetic Ingredient Review) has assessed benzalkonium chloride-type compounds and found them safe at reported use concentrations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Lauralkonium Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 31 mg/kg bw/day oral rat oral REACH
NOEL 500 ppm oral rat oral REACH

Expert Verdict

Skin and eye irritant at elevated concentrations. Contact sensitization potential. As with all cationic surfactants, toxicity increases with concentration; safe within established use levels. Identical quaternary ammonium structure to lauralkonium bromide but with chloride counterion. The chloride salt is more commonly used commercially. Offers dual functionality as both a preservative and an antistatic/conditioning agent

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Concern Level: High

Regulatory Flags

potential-allergen preservative

Frequently Asked Questions

Is Lauralkonium Chloride safe in cosmetics?

Skin and eye irritant at elevated concentrations. Contact sensitization potential. As with all cationic surfactants, toxicity increases with concentration; safe within established use levels. Identical quaternary ammonium structure to lauralkonium bromide but with chloride counterion. The chloride salt is more commonly used commercially. Offers dual functionality as both a preservative and an antistatic/conditioning agent The EU classifies Lauralkonium Chloride as "permitted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Lauralkonium Chloride allowed in the EU?

Lauralkonium Chloride EU regulatory status: permitted. Maximum allowed concentration: 0.1%. This is based on EU Regulation 1223/2009 and its amendments.

What does Lauralkonium Chloride do in cosmetics?

Lauralkonium Chloride functions as: Antistatic (reduces electrostatic charges in hair) and preservative (protects products from microbial spoilage). It is classified as a cosmetic ingredient in our database. CAS number: 139-07-1.

What is the Margin of Safety for Lauralkonium Chloride?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Lauralkonium Chloride?

The NOAEL (No Observed Adverse Effect Level) for Lauralkonium Chloride is 31 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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