Moderate Cosmetic Ingredient Sensitization Data

Calcium Paraben

INCI: CALCIUM PARABEN

CAS Number
69056-18-8
Function
Preservative (antimicrobial)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
EU Max Conc. 0.4%
🇺🇸 US Status permitted
US Notes Adequate at ≤0.4%. SCCS has evaluated and confirmed MoS ≥100 for 4-hydroxybenzoic acid salts at permitted levels.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Calcium Paraben based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
preservative
EU Allergen Listed
no
Patch Test Positive Rate
0.1%
Cross-reactivity Group
paraben-group
Reaction Type
contact-dermatitis

Source: ESSCA; IVDK; SCCS/1348/10

Expert Verdict

Calcium paraben is permitted at maximum 0.4% acid-equivalent; endocrine disruption potential is lower than propyl/butylparaben esters; molecular weight conversion required for PIF documentation; restricted in children's products in nappy area when combined with other parabens; allergen monitoring recommended.

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen preservative

Frequently Asked Questions

Is Calcium Paraben safe in cosmetics?

Calcium paraben is permitted at maximum 0.4% acid-equivalent; endocrine disruption potential is lower than propyl/butylparaben esters; molecular weight conversion required for PIF documentation; restricted in children's products in nappy area when combined with other parabens; allergen monitoring recommended. The EU classifies Calcium Paraben as "permitted". Safety rating: MODERATE.

Is Calcium Paraben allowed in the EU?

Calcium Paraben EU regulatory status: permitted. Maximum allowed concentration: 0.4%. This is based on EU Regulation 1223/2009 and its amendments.

What does Calcium Paraben do in cosmetics?

Calcium Paraben functions as: Preservative (antimicrobial). It is classified as a cosmetic ingredient in our database. CAS number: 69056-18-8.

What is the Margin of Safety for Calcium Paraben?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Calcium Paraben compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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