Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Caprolactam. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 0.10000000149 % | oral | dog | Subchronic | COSMOS_DB |
| LOAEL | 0.5 % | oral | dog | Subchronic | COSMOS_DB |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Questionable cosmetic ingredient — primarily an industrial monomer. If present as residual from Nylon polymers, must be controlled to ppm levels. Oral LD50 ~1g/kg (rat). Irritant classification. Reproductive toxicity data should be reviewed.
Regulatory Flags
Frequently Asked Questions
Is Caprolactam safe in cosmetics?
Questionable cosmetic ingredient — primarily an industrial monomer. If present as residual from Nylon polymers, must be controlled to ppm levels. Oral LD50 ~1g/kg (rat). Irritant classification. Reproductive toxicity data should be reviewed. The EU classifies Caprolactam as "permitted". Safety rating: POOR. 2 toxicological study endpoint(s) are available in our database.
Is Caprolactam allowed in the EU?
Caprolactam EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Caprolactam do in cosmetics?
Caprolactam functions as: Not a standard cosmetic active — primarily an industrial monomer (Nylon-6 precursor). If present in cosmetics, it would be as a residual monomer from Nylon-based polymers.. It is classified as a cosmetic ingredient in our database. CAS number: 105-60-2.
What is the Margin of Safety for Caprolactam?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Caprolactam?
The NOAEL (No Observed Adverse Effect Level) for Caprolactam is 0.10000000149 % based on a Subchronic study via oral route in dog. A total of 2 study endpoints are available. Source: COSMOS_DB.
Is Caprolactam classified as hazardous under GHS?
Caprolactam carries a GHS signal word of "WARNING". Hazard statements: Harmful if swallowed Causes skin and eye irritation May cause drowsiness or dizziness. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Compliance Tools
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Related Ingredients
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