Moderate Cosmetic Ingredient NOAEL Data GHS Classified

Caprylyl Alcohol

INCI: CAPRYLYL ALCOHOL

CAS Number
111-87-5
Function
Masking, Perfuming, Emollient, Viscosity Controlling
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes GRAS (Generally Recognized as Safe); also approved as indirect food additive

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Caprylyl Alcohol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 2564 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB
NOAEL 650 mg/kg bw/day oral rat Developmental COSMOS_DB

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes and respiratory tract. The substance is mildly irritating to the skin. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.
Long-term Exposure Effects
The substance defats the skin, which may cause dryness or cracking.
Routes of Exposure
The substance can be absorbed into the body by inhalation and by ingestion.

Expert Verdict

Well-established safety profile; mild skin/eye irritant at high concentrations; CIR assessed as safe

⚠️
Concern Level: Moderate

Regulatory Flags

fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Caprylyl Alcohol safe in cosmetics?

Well-established safety profile; mild skin/eye irritant at high concentrations; CIR assessed as safe The EU classifies Caprylyl Alcohol as "restricted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Caprylyl Alcohol allowed in the EU?

Caprylyl Alcohol EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Caprylyl Alcohol do in cosmetics?

Caprylyl Alcohol functions as: Masking, Perfuming, Emollient, Viscosity Controlling. It is classified as a cosmetic ingredient in our database. CAS number: 111-87-5.

What is the Margin of Safety for Caprylyl Alcohol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Caprylyl Alcohol?

The NOAEL (No Observed Adverse Effect Level) for Caprylyl Alcohol is 2564 mg/kg bw/day based on a Special Toxicology Study study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

Compliance Tools

Check Caprylyl Alcohol compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Methyl-Methylene-Octadiene Alpha-Terpineols
Moderate
1-Penten-3-ol
Moderate
2-Ethylhexanol
Good
Polygonum Multiflorum Root Water
Good
3-Ethoxy-1,1,5-Trimethylcyclohexane
Good
Browse all 30,000+ ingredients →
📱

Is Caprylyl Alcohol in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Caprylyl Alcohol in your formulation.

Ingredient Decoder MoS Calculator