Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Caprylyl Pyrrolidone. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 30 mg/kg bw/day | oral | code:3544 | oral | REACH |
| NOAEL | 30 mg/kg bw/day | oral | dog | oral | REACH |
| NOEL | 600 ppm | oral | rat | oral | REACH |
Expert Verdict
Enhances transdermal penetration of co-formulants; potential irritant at high concentrations
Regulatory Flags
Frequently Asked Questions
Is Caprylyl Pyrrolidone safe in cosmetics?
Enhances transdermal penetration of co-formulants; potential irritant at high concentrations The EU classifies Caprylyl Pyrrolidone as "restricted". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.
Is Caprylyl Pyrrolidone allowed in the EU?
Caprylyl Pyrrolidone EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Caprylyl Pyrrolidone do in cosmetics?
Caprylyl Pyrrolidone functions as: Surfactant, foaming, cleansing, permeation enhancer, antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 2687-94-7.
What is the Margin of Safety for Caprylyl Pyrrolidone?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Caprylyl Pyrrolidone?
The NOAEL (No Observed Adverse Effect Level) for Caprylyl Pyrrolidone is 100 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
Check Caprylyl Pyrrolidone compliance across multiple jurisdictions:
Related Ingredients
Is Caprylyl Pyrrolidone in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Caprylyl Pyrrolidone in your formulation.