Is Lauryl Pyrrolidone safe in cosmetics?
Lauryl Pyrrolidone has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Lauryl Pyrrolidone
Also known as: N-Lauryl-2-pyrrolidone, BRN 0155011, N-Dodecylpyrrolidinone, UNII-3P14VW8FNY
INCI: LAURYL PYRROLIDONE
Lauryl Pyrrolidone (CAS 2687-96-9) is a cosmetic cosmetic ingredient functioning as Surfactant — cleansing agent, foam stabilizer, conditioning agent, solvent,. Reported NOAEL =30 mg/kg bw/day in Dog (ECHA); EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 2687-96-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Lauryl Pyrrolidone is prohibited in EU cosmetics but has active industrial GHS classifications (H314, H317, H318, H400, H410, H373).
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Surfactant — cleansing agent, foam stabilizer, conditioning agent, solvent, penetration enhancer
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
1-dodecylpyrrolidin-2-one
InChIKey
NJPQAIBZIHNJDO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted — no specific CFR restriction; FDA UNII: 3P14VW8FNY
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Lauryl Pyrrolidone.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Lauryl Pyrrolidone. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =30 mg/kg bw/day | oral | Dog | subchronic | ECHA |
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Danger
Pictograms
CorrosiveHarmful / IrritantEnvironmental Hazard
Hazard Class and Category
Skin Corr. 1B; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1
Hazard Statements
- H314 Causes severe skin burns and eye damage
- H317 May cause an allergic skin reaction
- H400 Very toxic to aquatic life
- H410 Very toxic to aquatic life with long lasting effects
Inserted via ATP: CLP00
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Dispersing agent
Plasticizer
Softener and conditioner
Solvent
Surfactant (surface active agent)
Wetting agent (non-aqueous)
Expert Verdict
Expert safety assessment and concern-level summary for Lauryl Pyrrolidone.
Regulatory Flags
potential-allergen
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Lauryl Pyrrolidone by CAS number or substance name.
Studies
1
Lowest NOAEL
30 mg/kg bw/day
Highest NOAEL
30 mg/kg bw/day
ECHA
Known Synonyms
N-Lauryl-2-pyrrolidone
BRN 0155011
N-Dodecylpyrrolidinone
UNII-3P14VW8FNY
Chemical Function
Surfactant (surface active agent)
Cleaning agent
Softener and conditioner
Solvent
Plasticizer
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3186490
Frequently Asked Questions
Is Lauryl Pyrrolidone allowed in the EU?
Lauryl Pyrrolidone EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Lauryl Pyrrolidone do in cosmetics?
Lauryl Pyrrolidone functions as: Surfactant — cleansing agent, foam stabilizer, conditioning agent, solvent, penetration enhancer. It is classified as a cosmetic ingredient in our database. CAS number: 2687-96-9.
What is the NOAEL for Lauryl Pyrrolidone?
The NOAEL (No Observed Adverse Effect Level) for Lauryl Pyrrolidone is =30 mg/kg bw/day based on a subchronic study via oral route in Dog. Source: ECHA.
Is Lauryl Pyrrolidone used outside cosmetics?
Lauryl Pyrrolidone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Lauryl Pyrrolidone have different safety status in cosmetics vs industrial chemicals?
Lauryl Pyrrolidone is prohibited in EU cosmetics but has active industrial GHS classifications (H314, H317, H318, H400, H410, H373).
Compliance Tools
Check Lauryl Pyrrolidone compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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