Excellent Cosmetic Ingredient NOAEL Data

Chamomilla Recutita Flower Water

INCI: CHAMOMILLA RECUTITA (MATRICARIA) FLOWER WATER

Chamomilla Recutita Flower Water (CAS 84082-60-0) is a cosmetic cosmetic ingredient functioning as Masking; Skin conditioning; Soothing. Aqueous distillate obtained by steam. Reported NOAEL =200 mg/kg/d in rat (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 84082-60-0 →

Auto-generated CPSR Part A draft with source citations
Function
Masking; Skin conditioning; Soothing. Aqueous distillate obtained by steam distillation of fresh Matricaria recutita flowers. Contains water-soluble phenolic compounds including quercetin and luteolin. Provides anti-inflammatory, anti-aging, and calming activity; suitable for sensitive, rosacea, eczema, and acne-prone skin. Commonly used as a hydrosol in toners, mists, and baby care.
Safety Rating
EXCELLENT

Chemistry & Identifiers

EC Number
282-006-5

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes No specific FDA concentration limit for cosmetic use. Included in the CIR amended safety assessment (2018) alongside other Chamomilla recutita-derived ingredients; Expert Panel concluded safe as used. Widely used in infant and sensitive skin formulations, indicating strong safety acceptance.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Chamomilla Recutita Flower Water.

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Toxicological Studies

4 study endpoints found for Chamomilla Recutita Flower Water. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =200 mg/kg/d oral rat oral toxicity CIR_vision_codex
NOAEL =200 mg/kg/d oral rat oral toxicity CIR_vision_codex
NOAEL =200 mg/kg/d oral rat oral toxicity CIR_vision_codex
NOAEL =200 mg/kg/d oral rat oral toxicity CIR_vision_codex

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Biocide
Regulatory List Membership (2)
EU Regulated in Personal Care EU Restricted for Children (Cosmetics)

Expert Verdict

Expert safety assessment and concern-level summary for Chamomilla Recutita Flower Water.

Regulatory Flags

skin-conditioning soothing anti-inflammatory hydrosol baby-safe sensitive-skin cir-affirmed-safe asteraceae-family eu_children_restricted

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Chamomilla Recutita Flower Water by CAS number or substance name.

Studies
4
Lowest NOAEL
200 mg/kg/d
Highest NOAEL
200 mg/kg/d
CIR_vision_codex

Chemical Function

Deodorizer Softener and conditioner Fragrance

Regulatory Lists

children; Europe; Personal care children; Europe; Personal care - hair styling and care - shampoo children; Europe; Personal care - specialized bath products - bubble bath children; Europe; Personal care - dental care - toothpaste Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations
58
View full pharmaceutical profile →

Frequently Asked Questions

Is Chamomilla Recutita Flower Water safe in cosmetics?

Chamomilla Recutita Flower Water has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 4 toxicological study endpoint(s) are available in our database.

Is Chamomilla Recutita Flower Water allowed in the EU?

Chamomilla Recutita Flower Water EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Chamomilla Recutita Flower Water do in cosmetics?

Chamomilla Recutita Flower Water functions as: Masking; Skin conditioning; Soothing. Aqueous distillate obtained by steam distillation of fresh Matricaria recutita flowers. Contains water-soluble phenolic compounds including quercetin and luteolin. Provides anti-inflammatory, anti-aging, and calming activity; suitable for sensitive, rosacea, eczema, and acne-prone skin. Commonly used as a hydrosol in toners, mists, and baby care.. It is classified as a cosmetic ingredient in our database. CAS number: 84082-60-0.

What is the NOAEL for Chamomilla Recutita Flower Water?

The NOAEL (No Observed Adverse Effect Level) for Chamomilla Recutita Flower Water is =200 mg/kg/d based on a oral toxicity study via oral route in rat. A total of 4 study endpoints are available. Source: CIR_vision_codex.

Is Chamomilla Recutita Flower Water used outside cosmetics?

Chamomilla Recutita Flower Water also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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