Moderate Cosmetic Ingredient

Chlorella Vulgaris Methionyl sh-Polypeptide-14 Hexapeptide-40

INCI: CHLORELLA VULGARIS METHIONYL SH-POLYPEPTIDE-14 HEXAPEPTIDE-40

CAS Number
Not assigned
Function
Skin conditioning (bioengineered peptide complex — EGF-related growth factor produced in Chlorella expression system)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FDA — no specific restriction; not independently CIR-reviewed; recombinant peptides fall under general cosmetic ingredient safety obligations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Bioengineered growth-factor analog — regulatory authorities increasingly scrutinizing EGF-like peptides for potential proliferative effects; requires genotoxicity and cell proliferation data for EU CPSR; GMO-derived production may trigger additional EU regulatory requirements

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Concern Level: Moderate

Frequently Asked Questions

Is Chlorella Vulgaris Methionyl sh-Polypeptide-14 Hexapeptide-40 safe in cosmetics?

Bioengineered growth-factor analog — regulatory authorities increasingly scrutinizing EGF-like peptides for potential proliferative effects; requires genotoxicity and cell proliferation data for EU CPSR; GMO-derived production may trigger additional EU regulatory requirements The EU classifies Chlorella Vulgaris Methionyl sh-Polypeptide-14 Hexapeptide-40 as "permitted". Safety rating: MODERATE.

Is Chlorella Vulgaris Methionyl sh-Polypeptide-14 Hexapeptide-40 allowed in the EU?

Chlorella Vulgaris Methionyl sh-Polypeptide-14 Hexapeptide-40 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Chlorella Vulgaris Methionyl sh-Polypeptide-14 Hexapeptide-40 do in cosmetics?

Chlorella Vulgaris Methionyl sh-Polypeptide-14 Hexapeptide-40 functions as: Skin conditioning (bioengineered peptide complex — EGF-related growth factor produced in Chlorella expression system). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Chlorella Vulgaris Methionyl sh-Polypeptide-14 Hexapeptide-40?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Chlorella Vulgaris Methionyl sh-Polypeptide-14 Hexapeptide-40 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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